Instinct MI250X

Best local AI models for this GPU

VRAM
128 GB
Bandwidth
3277 GB/s
Vendor
AMD
Compatible Models
29

Top Compatible Models

Top 10 models ranked by performance. Click any model to expand details or view full compatibility.

Memory Usage94.1 GB
Weights
KV Cache
Overhead
Context Length32,768 tokens
Install with Ollama:
ollama run gpt-oss:120b-q5_k_m
View full compatibility
Memory Usage44.3 GB
Weights
KV Cache
Overhead
Context Length163,840 tokens
Install with Ollama:
ollama run deepseek-r1:70b
View full compatibility
Memory Usage44.3 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run llama3.3:70b
View full compatibility
Memory Usage45.5 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run qwen2.5:72b
View full compatibility
Memory Usage44.3 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run llama3.1:70b
View full compatibility
Memory Usage29.6 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run qwen3:32b-q6_k
View full compatibility
Memory Usage29.1 GB
Weights
KV Cache
Overhead
Context Length16,384 tokens
Install with Ollama:
ollama run gemma3:27b-q6_k
View full compatibility
Memory Usage29.6 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run qwen2.5:32b-q6_k
View full compatibility
Memory Usage29.6 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run qwen2.5-coder:32b-q6_k
View full compatibility
Memory Usage22.5 GB
Weights
KV Cache
Overhead
Context Length131,072 tokens
Install with Ollama:
ollama run mistral-small:24b-q6_k
View full compatibility